Benefits of Libido¹ Support Caps
Introduction
Libido¹ Support Caps contain a blend of herbal extracts (Muira puama, Panax ginseng, Ginkgo biloba, Tribulus terrestris) along with Vitamin E and Zinc. This report summarizes the potential health benefits of these ingredients, primarily focusing on their roles in sexual function and overall well-being, based on available medical literature.
Key Findings
Tribulus terrestris and Panax ginseng have shown significant positive effects on female sexual function, including desire, arousal, and orgasm [1].
A combination of L-Citrulline, L-Carnitine, Eruca vesicaria, Panax ginseng, Tribulus terrestris, Turnera diffusa, Taurine, Vitamin E, and Zinc (Icarifil®) improved erectile function in men with mild-to-moderate ED, particularly when combined with daily tadalafil [2].
A herbal formulation of Muira and Ginkgo biloba demonstrated improved sexual desire, intercourse frequency, and satisfaction in 65% of premenopausal and postmenopausal women with low sex drive after 1 month of treatment [3].
Evidence on Sexual Function
Tribulus terrestris has been shown to improve erectile function in men with erectile dysfunction (ED). A systematic review and meta-analysis of eight studies found that Tribulus terrestris significantly elevated IIEF-5 scores by MD 4.21 and IIEF-15 scores by MD 15.88 compared to pre-supplementation levels. It also outperformed placebo with an IIEF-5 MD 3.23 and IIEF-15 MD 14.44 [4]. For women, a systematic review and meta-analysis of 20 studies indicated that Tribulus terrestris significantly improved overall female sexual function (SMD = 1.12), sexual arousal (SMD = 1.03), sexual desire (SMD = 1.08), and sexual orgasm (SMD = 0.51) compared to placebo [1].
Panax ginseng has also ;demonstrated benefits for female sexual dysfunction, with significant improvements in sexual arousal (SMD = 0.54) and sexual desire (SMD = 0.59) compared to placebo [1]. In male mice, ;herbal medicine containing Tribulus terrestris and Panax ginseng increased introduction and climbing behavior after 14 days ;of treatment with 2x doses [5].
A unique herbal formulation containing Muira puama and Ginkgo biloba was assessed in 202 healthy women with low sex drive. After 1 month of treatment, 65% of the participants showed significantly higher average total scores from baseline in various aspects of their sex life, including sexual desires, intercourse, fantasies, and orgasm intensity [3].
Other Potential Health Benefits
Ginkgo biloba is rich in antioxidants and may help mitigate inflammation and enhance cardiovascular, cognitive, and ocular health. It is also used for respiratory, cardiovascular, and neurological problems [6].
Tribulus terrestris possesses a range of pharmacological activities, including aphrodisiac, immunomodulatory, cardioprotective, antidiabetic, anti-inflammatory, and hepatoprotective properties. It is also popular in sports for potentially boosting the central nervous system [7] [8].
Zinc and Vitamin E are components of the Icarifil® mixture, which has been studied for its ability to increase muscle epithelium cell proliferation, cell turgor, and reduce reactive oxygen species (ROS) that contribute to ED pathophysiology. Icarifil® also showed efficacy in inhibiting PDE5 levels by over 65% compared to control [9]. A study in male rabbits showed that Tribulus terrestris with or without Vitamin E significantly increased hemoglobin, hematocrit, total protein, albumin, and globulin levels [10].
Conclusion
The ingredients in Libido¹ Support Caps, including Muira puama, Panax ginseng, Ginkgo biloba, Tribulus terrestris, Vitamin E, and Zinc, collectively offer a range of potential health benefits, particularly in improving sexual function for both men and women. Tribulus terrestris and Panax ginseng show promising results in enhancing various aspects of female sexual function and male erectile function. Combinations of these ingredients have also demonstrated efficacy in improving sexual desire and performance. Additionally, Ginkgo biloba and Tribulus terrestris contribute to broader health benefits such as antioxidant activity, anti-inflammatory effects, and cardiovascular support.
References:
1) N Sha'ari et al. Beneficial effects of natural products on female sexual dysfunction: A systematic review and meta-analysis. Phytomedicine: international journal of phytotherapy and phytopharmacology (2021). https://pubmed.ncbi.nlm.nih.gov/34638031
2) T Cai et al. Icarifil® in Association with Daily Use of Tadalafil (5 mg) versus Standard Tadalafil Daily Dose (5 mg) or Alone: Results from a Controlled, Randomized Clinical Trial. Journal of clinical medicine (2024). https://pubmed.ncbi.nlm.nih.gov/38731094
3) J Waynberg et al. Effects of Herbal vX on libido and sexual activity in premenopausal and postmenopausal women. Advances in therapy (2001). https://pubmed.ncbi.nlm.nih.gov/11186145
4) S Suharyani et al. Tribulus terrestris for management of patients with erectile dysfunction: a systematic review and meta-analysis of randomized trials. International journal of impotence research (2025). https://pubmed.ncbi.nlm.nih.gov/40360723
5) Aguslina Kirtishanti et al. Herbal Medicine Used to Increase the Libido of Male Mice (Mus musculus): Tribulus terrestris and Panax ginseng. JURNAL ILMU KEFARMASIAN INDONESIA (2023). http://dx.doi.org/10.35814/jifi.v21i2.1485
6) Alfi Shahrin et al. Health benefits and future perspectives of Ginkgo biloba. Journal of Multidisciplinary Sciences (2024). https://doi.org/10.33888/jms.2024.626
7) Haiyan Zhang et al. Study of puncture vine (Tribulus terrestris L.), and the important roles of its chemical ingredients. Notulaeb ;Scientia Biologicae (2025). https://doi.org/10.55779/nsb17112194/
8) M Saeed et al. Promising phytopharmacology, nutritional potential, health benefits, and traditional usage of Tribulus terrestris L. herb. Heliyon (2024). https://pubmed.ncbi.nlm.nih.gov/38375303
9) Chiara Amante et al. Icarifil, a Natural Mixture Based on L-Citrulline and L-Carnitine as a Novel Multicomponent Nutraceutical to Modulate ROS and PDE5. Applied Sciences (2023). https://doi.org/10.3390/app132212358
10) Hamzah R. Kh. et al. Synergistic Effect of Raw Tribulus terrestris With Vitamin E on Some Biochemical and Physiological Parameters in local Male Rabbits. Al-Anbar Journal of Veterinary Sciences (2022). https://doi.org/10.37940/ajvs.2022.15.2.5