Benefits of Cell Shield Antioxidant Complex Caps
Key Findings
Supplementation with various antioxidant vitamins (beta-carotene, C, E) and trace elements (zinc, selenium) has been shown to increase serum concentrations of these nutrients and improve antioxidant system markers in adults [1].
Antioxidant-multivitamin complexes containing ingredients like L-arginine, N-acetylcysteine, selenium, zinc, and vitamins C and E have demonstrated positive effects on male fertility parameters, including sperm concentration and motility [2] [3].
Certain antioxidant combinations, including zinc, selenium, beta-carotene, and vitamins A and E, may reduce oxidative stress and potentially lower the risk of advanced age-related macular degeneration in high-risk individuals [4] [5].
Introduction
The Cell Shield Antioxidant Complex contains a blend of vitamins (E, B complex, C, beta-carotene), minerals (magnesium, copper, zinc, manganese, selenium), citrus bioflavonoids, and other compounds such as bromelain, papain, L-arginine, and N-acetyl-L-cysteine. These ingredients are primarily recognized for their antioxidant properties and potential roles in various physiological processes. This report summarizes the documented benefits associated with these components based on available medical literature.
Main Text
Antioxidant and Immune Support
A randomized double-blind trial involving 401 subjects (men aged 45-60 and women aged 35-60) showed that daily supplementation with beta-carotene (6 mg), vitamin C (120 mg), vitamin E (30 mg), zinc (20 mg), and selenium (100 micrograms) significantly increased mean serum concentrations of these nutrients after 3 months. This supplementation also led to a significant increase in plasma and red cell glutathione peroxidase (GPx) activity, indicating improved antioxidant status [1]. Similarly, a pilot trial with 16 participants found that a multivitamin, multimineral, herbal, essential oil-infused supplement, which included vitamin E, improved serum vitamin E levels and antioxidant status after two months [6]. The components of the Cell Shield Antioxidant Complex, such as N-acetylcysteine (NAC), selenium, zinc, and B and C vitamins, are also noted for their immune-stimulating properties [7]. NAC, in particular, has been shown to significantly reduce X-ray induced DNA double-strand breaks in human blood lymphocytes, demonstrating potential radioprotective effects [8].
Male Fertility and Reproductive Health
A retrospective case-control study with 300 infertile men investigated the effects of a daily antioxidant-multivitamin complex containing astaxanthin, Coenzyme Q10, L-arginine (250mg), L-carnitine, selenium (100mcg), zinc (10mg), folic acid (400mcg), vitamin E (100mg), and vitamin C (100mg) over four months. This supplementation resulted in statistically significant increases in semen volume (2.21 ml to 3.05 ml; p=.004), sperm concentration (9.60 million/ml to 14.10 million/ml; p=.000), progressive sperm motility (16.50% to 26.65%; p=.000), and sperm viability (48% to 68%; p=.001). The treatment also significantly reduced the number of patients with abnormal sperm morphology (77% to 61%; p=.002) [2]. A systematic review further supports that antioxidant supplementation, including carnitines, vitamins E and C, N-acetylcysteine, coenzyme Q10, selenium, zinc, and folic acid, appears to have a positive effect on male fertility parameters and live-birth rates [3].
Other Potential Health Benefits
Antioxidant micronutrients, including carotene, vitamin E, and vitamin C, have been associated with reduced risks of cancer and ischemic heart disease in epidemiological studies when plasma levels exceed certain thresholds [9]. A French trial indicated that a combination of vitamin C, vitamin E, beta-carotene, selenium, and zinc reduced cancer risk in men, though not in women [5]. For age-related macular degeneration (AMD), zinc and other antioxidants have shown benefits in preventing advanced stages of the disease in high-risk individuals [5]. Additionally, NAC supplementation has been linked to improvements in exercise performance and glutathione homeostasis in adult men, with no serious adverse events reported [10].
Conclusions
The Cell Shield Antioxidant Complex, with its array of vitamins, minerals, and other antioxidant compounds, offers several potential health benefits. These include enhancing overall antioxidant status and immune function, significantly improving male fertility parameters, and potentially reducing the risk of certain chronic diseases like cancer in men and advanced age-related macular degeneration in high-risk populations. While individual components have demonstrated efficacy in various studies, further research is often needed to confirm optimal combinations and dosages for specific health outcomes.
References:
1) P Preziosi et al. Effects of supplementation with a combination of antioxidant vitamins and trace elements, at nutritional doses, on biochemical indicators and markers of the antioxidant system in adult subjects. Journal of the American College of Nutrition (1998). https://pubmed.ncbi.nlm.nih.gov/9627910/
2) Pınar Tuğçe Özer et al. Effect of an antioxidant agent-multivitamin complex food supplement on spermiogram in infertile men. Aegean Journal of Obstetrics and Gynecology (2023). http://dx.doi.org/10.46328/aejog.v5i2.137/
3) F Dimitriadis et al. Antioxidant Supplementation on Male Fertility-A Systematic Review. Antioxidants (Basel, Switzerland) (2023). https://pubmed.ncbi.nlm.nih.gov/37107211/
4) U Cornelli et al. Bioavailability and antioxidant activity of some food supplements in men and women using the D-Roms test as a marker of oxidative stress. The Journal of nutrition (2001). https://pubmed.ncbi.nlm.nih.gov/11739867/
5) HY Huang et al. Multivitamin/mineral supplements and prevention of chronic disease. Evidence report/technology assessment (2007). https://pubmed.ncbi.nlm.nih.gov/17764205/
6) X Han et al. Evaluation of the Health Benefits of a Multivitamin, Multimineral, Herbal, Essential Oil-Infused Supplement: A Pilot Trial. Journal of dietary supplements (2017). https://pubmed.ncbi.nlm.nih.gov/28692411/
7) Jerry T. Thornthwaite et al. Abstract 621: The importance of antioxidant, antiangiogenesis and immune stimulation in cancer. Cancer Research (2012). https://doi.org/10.1158/1538-7445.am2012-621/
8) NS Bicheru et al. Effect of Different Antioxidants on X-ray Induced DNA Double-strand Breaks Using γ-H2AX in Human Blood Lymphocytes. Health physics (2020). https://pubmed.ncbi.nlm.nih.gov/32483045/
9) KF Gey et al. Prospects for the prevention of free radical disease, regarding cancer and cardiovascular disease. British medical bulletin (1993). https://pubmed.ncbi.nlm.nih.gov/8221032/
10) D Fernández-Lázaro et al. Influence of N-Acetylcysteine Supplementation on Physical Performance and Laboratory Biomarkers in Adult Males: A Systematic Review of Controlled Trials. Nutrients (2023). https://pubmed.ncbi.nlm.nih.gov/37299425/